Multi-image Analysis GUI
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Disease Analysis

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Description: The Disease Analysis plugin performs regional behavior analysis based on a user selected brain region of interest (ROI). The image where the ROI is defined must be in the Talairach brain space before processing. You should verify that the origin is correctly positioned (press 'o' key in Mango), since analysis is coordinate based. Talairach spatial normalization can be done using Mango's SN plugin for anatomical images. If your image was aligned using the MNI brain template you can use the MNI-to-Tal transform, which is an option in the transform menu (Mango v2.6 and later).

Results of Disease Analysis are presented for BrainMap's ICD-10 codes and Diagnoses. Only z-scores >=3.0 are considered significant (p<=0.05 with Bonferroni correction for multiple comparisons). A behavior profile chart and z-score ranked table (figure) are provided to assist with interpretation.

Publication: Lancaster JL, Laird AR, Eickhoff SB, Martinez MJ, Fox PM, Fox PT. Automated regional behavioral analysis for human brain imaging. Front Neuroinform 6, Epub Aug 28 2012. [PDF] [DOI] [PubMed]

Version History:
3.0 (06-14-2023) — Updated to current data from BrainMap VBM and VBP databases
2.0.1 (02-10-2019) — Resized list columns to give the Disease list more space.
2.0 (02-09-2018) — Adding a column for ICD-10 Codes, and color-coding for F and G codes.
1.0 (10-25-2018) — Initial public release.